CASCADE-CATALYSED NANOCARRIER DEGRADATION FOR REGULATING METABOLISM HOMEOSTASIS AND ENHANCING DRUG PENETRATION ON BREAST CANCER

Cascade-catalysed nanocarrier degradation for regulating metabolism homeostasis and enhancing drug penetration on breast cancer

Abstract The abnormal structure of tumor vascular seriously hinders the delivery and deep penetration of drug in tumor therapy.Herein, an integrated and tumor microenvironment (TME)-responsive nanocarrier is designed, which can dilate vessle and improve the drug penetration by in situ releasing nitric oxide (NO).Briefly, S-nitroso-glutathione (GSNO

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Genomic Analyses of Methicillin-Susceptible and Methicillin-Resistant Staphylococcus pseudintermedius Strains Involved in Canine Infections: A Comprehensive Genotypic Characterization

Staphylococcus pseudintermedius is frequently associated with several bacterial infections in dogs, highlighting a One Health concern due to the zoonotic potential.Given the clinical significance of this pathogen, we performed comprehensive genomic analyses of 28 S.pseudintermedius strains isolated from canine infections throughout whole-genome seq

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Florabank1: a grid-based database on vascular plant distribution in the northern part of Belgium (Flanders and the Brussels Capital region)

Florabank1 is a database that contains distributional data on the wild flora (indigenous species, archeophytes and naturalised aliens) of Flanders and the Brussels Capital Region.It holds about 3 million records of vascular plants, dating from 1800 till present.Furthermore, it Glandulars includes ecological data on vascular plant species, redlist c

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